TCT-53 Thromboembolic event rate is elevated with lower adherence to warfarin and NOACs
نویسندگان
چکیده
منابع مشابه
Well-managed warfarin is superior to NOACs.
Limitations of the NOAC randomized controlled trial (RCT) evidence base The multinational NOAC RCTs demonstrated noninferiority to warfarin at and below the following mean international normalized ratio (INR) time in therapeutic range (TTR): 64% for dabigatran in the RELY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial ; 55% for rivaroxaban in the Rocket-AF (Rivaroxaban Once ...
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BACKGROUND Warfarin has been the anticoagulant of choice for the prevention of ischaemic stroke in patients with atrial fibrillation (AF). Novel oral anticoagulants (NOACs) are increasingly used as an alternative. OBJECTIVES The objective of this review was to evaluate the efficacy and safety of the NOACs versus warfarin in patients with AF. SEARCH METHODS Medline, EMBASE and grey literatur...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2016
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2016.09.199